Members-only rates
4.8 / 5 Excellent

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Check in 3:00 PM
Check out 11:00 AM

About Hampton Inn & Suites St. Louis/South I-55

The Hampton Inn & Suites - Saint Louis South Interstate 55 is directly off Interstate 55, and 15 mi south of downtown St. Louis and its famous arch. Rooms at Hampton Inn & Suites - Saint Louis South Interstate 55 have flat-screen TVs. All rooms come furnished with a microwave, refrigerator, and work desk. A breakfast buffet is served every morning and newspapers are delivered to rooms at the Hampton Inn & Suites - Saint Louis South Interstate 55. Guests can relax in the indoor pool and spa bath after a long day or a workout in the hotel’s fitness center. The hotel offers many convenient amenities, such as a business center, an ATM/cash machine, and dry cleaning. The St. Louis Zoo is 30 minutes away from the Saint Louis South Interstate 55 Hampton Inn & Suites. The hotel is 25 mi away from Cahokia Mounds State Park, a UNESCO World Heritage site that features the largest pre-Columbian city in North America. One of the largest breweries in the world, the Anheuser-Busch Brewery, is 20 mi away.

Amenities

  • 24-hour front desk
  • Meeting space
  • Fitness center
  • On-site dining
  • Café / coffee shop
  • Business center
  • Express check-in / check-out
  • Concierge
  • Dry cleaning
  • Self-service laundry
  • Luggage storage
  • Full kitchen / kitchenette
  • In-room refrigerator
  • Pool
  • Spa / sauna
  • Pet friendly
  • Family friendly
  • Wheelchair accessible
  • Smoke-free property
  • Air conditioning
  • Elevator
  • In-room safe

Reviews

4.8 / 5
Excellent 1001 reviews
  • Engine customer Oct 2026

    Jacuzzi tub in the room was great!

  • Engine customer Oct 2026

    Staff was extremely accommodating to assist in getting WiFi access due to computer problems. Zach, their IT

  • Engine customer Sep 2026

    Superb

  • Engine customer Sep 2026

    Superb

  • Engine customer Sep 2026

    Hotel location was easy to find. Property and parking lot were well lit, landscaped and clean. Room was clean, well maintained and comfortable. Staff was friendly, outgoing and helpful. Fresh-baked cookies and milk at 8pm every evening said, "We're glad you're here. Enjoy this bedtime snack."

  • Engine customer Sep 2026

    Our room was clean & well-maintained, with plenty of space. Having a small fridge & microwave was a plus. We took advantage of the pool while there... great after a long drive! Staff was friendly, & eager to help us navigate the area & choose a restaurant for dinner. On-site parking was easily accessible. Our stay was topped off with cookies in the evening & a full breakfast in the morning.

  • Engine customer Aug 2026

    Nicer than 4 star hotels I’ve stayed in!! The property was clean, the room was spacious, the breakfast was great, staff was super nice. One of the best hotels I’ve stayed in. Highly recommend!!

  • Engine customer Aug 2026

    Exceptional

  • Engine customer Aug 2026

    I’ve stayed there 3 times mainly because it’s close to my sick sister. I stayed and the room was hot due to a faulty thermostat. They gave me points instead of a refund. I did not use points. Very disappointing. The faulty a/c

  • Engine customer Aug 2026

    Very quiet area. The room so clean and staffs were super helpful. Will be coming back.

  • Engine customer Aug 2026

    Very clean, safe, and comfortable!

  • Engine customer Aug 2026

    Exceptional

  • Engine customer Aug 2026

    Exceptional

  • Engine customer Aug 2026

    It was a comfortable stay and breakfast was great!

  • Engine customer Aug 2026

    The room was very spacious and had a separate sitting area. It was also very clean. Nothing

  • Engine customer Aug 2026

    Clean room, good breakfast and perfect location for out stay. Interstate was conveniently close. 2nd time staying those year and a solid choice both times

  • Engine customer Aug 2026

    Superb

  • Engine customer Aug 2026

    Great place clean rooms

  • Engine customer Aug 2026

    Everything. Nothing

  • Engine customer Aug 2026

    Great staff, very clean room and building.

Frequently asked questions about Hampton Inn & Suites St. Louis/South I-55

Does Hampton Inn & Suites St. Louis/South I-55 have free Wi-Fi?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free Wi-Fi for all guests. Free wired internet is also available in select rooms.
Does Hampton Inn & Suites St. Louis/South I-55 offer parking?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free parking on-site.
Does Hampton Inn & Suites St. Louis/South I-55 have meeting spaces, conference centers, or conference rooms?
Yes. Hampton Inn & Suites St. Louis/South I-55 features meeting spaces and dedicated conference rooms, suitable for corporate meetings and group gatherings. Banquet and reception facilities are also available.
Does Hampton Inn & Suites St. Louis/South I-55 have a fitness center?
Yes, Hampton Inn & Suites St. Louis/South I-55 features an on-site fitness center for guests. Additional wellness amenities include spa, pool.
Where is Hampton Inn & Suites St. Louis/South I-55 located, and how walkable is the area?
Hampton Inn & Suites St. Louis/South I-55 is located at 4200 Midamerica Lane, St. Louis, MO 63129. With a Walk Score of 43, the area is rated Car-Dependent. A car or rideshare is recommended for most trips in this area.

Why no public rates?

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