Members-only rates
4.8 / 5 Excellent

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Check in 3:00 PM
Check out 11:00 AM

About Hampton Inn & Suites St. Louis/South I-55

The Hampton Inn & Suites - Saint Louis South Interstate 55 is directly off Interstate 55, and 15 mi south of downtown St. Louis and its famous arch. Rooms at Hampton Inn & Suites - Saint Louis South Interstate 55 have flat-screen TVs. All rooms come furnished with a microwave, refrigerator, and work desk. A breakfast buffet is served every morning and newspapers are delivered to rooms at the Hampton Inn & Suites - Saint Louis South Interstate 55. Guests can relax in the indoor pool and spa bath after a long day or a workout in the hotel’s fitness center. The hotel offers many convenient amenities, such as a business center, an ATM/cash machine, and dry cleaning. The St. Louis Zoo is 30 minutes away from the Saint Louis South Interstate 55 Hampton Inn & Suites. The hotel is 25 mi away from Cahokia Mounds State Park, a UNESCO World Heritage site that features the largest pre-Columbian city in North America. One of the largest breweries in the world, the Anheuser-Busch Brewery, is 20 mi away.

Amenities

  • 24-hour front desk
  • Meeting space
  • Fitness center
  • On-site dining
  • Café / coffee shop
  • Business center
  • Express check-in / check-out
  • Concierge
  • Dry cleaning
  • Self-service laundry
  • Luggage storage
  • Full kitchen / kitchenette
  • In-room refrigerator
  • In-room microwave
  • Pool
  • Spa / sauna
  • Pet friendly
  • Family friendly
  • Wheelchair accessible
  • Public transit access
  • Airport shuttle
  • Smoke-free property
  • Air conditioning
  • Elevator

Reviews

4.8 / 5
Excellent 1001 reviews
  • Engine customer Aug 2026

    Everything was fine

  • Engine customer Aug 2026

    The only thing I would change was the pillow situation! The pillows hardly gave any support and we were unable to get extra.

  • Engine customer Aug 2026

    Nothin to report

  • Engine customer Jul 2026

    A big shout out to Priscilla and crew for her professionalism , warm and welcoming personality and kindness !!!

  • Engine customer Jul 2026

    Room was clean and breakfast was excellent. But bed was older and squeezing and pillows need to be replaced and the A/C only went to 68 would be the only negative.

  • Engine customer Jul 2026

    The hotel is very beautiful and modern. Our room was excellent! The beds are very comfortable, but most importantly the front desk staff are some of the most amazing and helpful people! And I would love to give a shout out to Priscilla, who was just very accommodating and very nice!! Bonus : the food is good !!

  • Engine customer Jul 2026

    Friendly staff, quiet, clean,safe, easy parking. Excellent breakfast. Would definitely stay there again.

  • Engine customer Jul 2026

    Excellent stay all around. Breakfast was on point

  • Engine customer Jul 2026

    Excellent place to stay. We need boat towing space and plenty of room. Excellent breakfast and space for it. Super friendly staff. Went to some baseball games and worked out great!

  • Engine customer Jul 2026

    The grounds of this hotel were very well kept, clean and I felt very safe walking around outside the hotel. There wasn’t anything I didn’t like about the hotel property.

  • Engine customer Jul 2026

    All the staff were so friendly. The ladies at breakfast (Kathy and Nancy) were so cheerful and helpful. These are the people who will make your day brighter. I like the bright room.

  • Engine customer Jul 2026

    There was security on property so you don't have to worry about your car being stolen or broken into. The hotel was clean and the staff was friendly. The rooms were nice as well I would definitely recommend

  • Engine customer Jul 2026

    The sheets on the bed were stained on the one bed. The housekeeper never came which isn't really an issue. One of the beds sounded like it was broken or breaking every time we would lay down.

  • Engine customer Jun 2026

    Very nice and comfortable

  • Engine customer Jun 2026

    Very spacious and clean room. Friendly staff and nice breakfast.

  • Engine customer Jun 2026

    Hotel was clean and the staff was polite and helpful. Breakfast was fair.

  • Engine customer Jun 2026

    We had to leave....

  • Engine customer Jun 2026

    Better quality of food.

  • Engine customer Jun 2026

    Location Check out staff great attitudes Check in staff. Terrible attitudes

  • Engine customer Jun 2026

    Very clean and comfortable

Frequently asked questions about Hampton Inn & Suites St. Louis/South I-55

Does Hampton Inn & Suites St. Louis/South I-55 have free Wi-Fi?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free Wi-Fi for all guests. Free wired internet is also available in select rooms.
Does Hampton Inn & Suites St. Louis/South I-55 offer parking?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free parking on-site.
Does Hampton Inn & Suites St. Louis/South I-55 have meeting spaces, conference centers, or conference rooms?
Yes. Hampton Inn & Suites St. Louis/South I-55 features meeting spaces and dedicated conference rooms, suitable for corporate meetings and group gatherings. Banquet and reception facilities are also available.
Does Hampton Inn & Suites St. Louis/South I-55 have a fitness center?
Yes, Hampton Inn & Suites St. Louis/South I-55 features an on-site fitness center for guests. Additional wellness amenities include spa, pool.
Where is Hampton Inn & Suites St. Louis/South I-55 located, and how walkable is the area?
Hampton Inn & Suites St. Louis/South I-55 is located at 4200 Midamerica Lane, St. Louis, MO 63129. With a Walk Score of 43, the area is rated Car-Dependent. A car or rideshare is recommended for most trips in this area.

Why no public rates?

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